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Case Report

A Case Report of VAC Dressing System Applied over a Lattisimus Dorsi(LD) Flap Reconstruction for a Crush Injury on the Lower Extremities: Indications, Technical Aspects and Outcomes


Stamatis Sapountzis ,

St. Luke’s Hospital, GR
About Stamatis
Dr. Stam (Stamatis Sapountzis) is Board Certified Plastic Surgeon based in Thessaloniki, Greece. After graduating from the Medical School of Aristotle University of Thessaloniki, Dr. Stam trained in General Surgery and Plastic Surgery in Greece. In 2010 he moved in S.Korea and worked as Microsurgical – Breast Fellow next to Prof. Heo Chan Yeong in Seoul National University Bundang Hospital, which is one the most prestigious hospitals in S. Korea and one of the few full digital hospitals in the world. In 2011 he continued his training in Taiwan next to Prof. Hung Chi Chen, in China Medical University Hospital in Taichung. During his 2 years stay, he enhanced his experience in advanced reconstructive microsurgery and performed more than 100 free flaps for head and neck reconstruction, breast, trunk and lower limb reconstruction. He showed special interest in Lymphedema Surgery using microsurgical techniques and he is one of the few surgeons in the world specialized in Vascularized Lymph Node Transfer. After 3 years in Asia, he moved in UK, as Microsurgical – Breast Fellow in Queen Victoria Hospital where he gained significant experience in in breast reconstruction using autologous tissue. From 2013 he is International Board of Director of NPO “Givemefive” with head quarter in Aurangabad (India), providing surgical assistance in economically underprivileged tribal population in Asia. Dr. Stam has published more 40 studies in International Scientific Journals about reconstructive and aesthetic surgery in cooperation with Universities in Brazil and USA, and attended several meetings in USA, UK, Taiwan, Korea and other places in the world. He is PhD candidate of Plastic Surgery at Aristotle University of Thessaloniki, studying the effect of tissue glue in microvascular anastomosis.
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Georgios Karamitros,

St. Luke’s Hospital, GR
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Vasileios Goulios,

St. Luke’s Hospital, GR
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Ioannis Rallis

Private Practice, GR
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Although VAC dressing system is a very reliable and effective way to support wound healing there are not many mentions in the literature that investigate the use of the VAC system over free flaps, especially for the reconstruction of injuries in the extremities.
In this case report we present the use of the VAC system over a mascolocutaneous latissimus dorsi(LD) that was was used to cover the extensive deficits on the left foot after a car accident. In this case the LD flap that was applied showed signs of venous congestion and even though venous re-anastomosis of the flap was used by inter-positioning a vein graft from the contra-lateral leg, still venous congestion was not resolved due to the increased interstitial pressure. With the low negative pressure provided by the VAC system, we managed to overcome the interstitial pressure and achieve adequate capillary perfusion and blood supply to the flap.

How to Cite: Sapountzis S, Karamitros G, Goulios V, Rallis I. A Case Report of VAC Dressing System Applied over a Lattisimus Dorsi(LD) Flap Reconstruction for a Crush Injury on the Lower Extremities: Indications, Technical Aspects and Outcomes. International Journal of Orthoplastic Surgery. 2018;1(3):101–5. DOI:
  Published on 10 Dec 2018
 Accepted on 07 Aug 2018            Submitted on 18 Feb 2018


Wound healing is a continuous and complex procedure which involves cell proliferation, cell migration and eventually the restoration and closure of the wound. Still, even though in our time, there is a plethora of treatment options for wound healing such as systemic and local antiseptic administration, different dressing types even hyperbarbaric oxygen; the treatment of chronic wounds is still an enigma for most surgeons [1].

However by 1993 a new solution has been suggested by Fleischmann [2] who introduced the idea that chronic wounds could be managed via negative pressure. This idea was eventually supported via experimental data from Argent [3, 4] in 1997 who published a study, in which he applied negative pressure coverings on injuries of the torso and the extremities. The aforementioned system is known as vacuum-assisted closure system (VAC) (San Antonio, Texas, USA).

Vacuum assisted closure (VAC) therapy is a trustworthy technique that is proven to support and to increase the blood perfusion of the dermal and sub-dermal tissue. It also, enhances the formation of granulation tissue while on the other hand it prevents the accumulation of interstitial fluid, exuded bacteria load and debrides to the wound [5, 6].

Parrett et. al. [7] published a study in 2006 in which he reports the use of the VAC system in order to reconstruct the soft tissue of injuries in the lower extremities. In his study Parrett mentioned an increased usage of the VAC system while the rates of infection, malnutrition/non-union and amputation remained the same and the need for re-operation declined.

However, the application of a VAC system over a free flap has not yet been widely reported in the literature as potential pressure over the flap can compromise its perfusion. Herein, we report a case of a crash injury of the foot, which was initially dealt with a free flap and split thickness skin grafts (STSG). The free flap supported with the VAC system after an infection which resulted into total graft loss. This case repost is presented according the consensus-based surgical case report guidelines [8].

Case report

Patient Information

47 year old female previously fit and well and with no medical co-morbitities was brought to the St. Lukas Hospital, by ambulance after a car accident. The patient had no past medical history, no previous surgical interventions and was not on any medication. She was also not allergic to any medication, she was not drinking and was not a smoker.

Clinical Findings, Diagnosis assessment and Therapeutic intervention

The 47 year old woman had sustained a crush injury of the left foot due to the car accident (Figure 1). After several surgical debridements and control of the local infection with antibiotics(co-amoxiclav), VAC therapy was applied for 2 weeks. The tissue loss was proximally 2/3 of the sole and the dorsal of the foot (Figure 2). Dr. Sapountzis (plastic surgeon), Dr. Goulios(orthopaedic surgeon), Dr. Rallis(orthopaedic surgeon) and Dr. Karamitros (surgical trainee) used a free mascolocutaneous lattisimus dorsi (LD) flap, which was transferred to cover the extensive deficits of the area. End-to-end arterial anastomosis was completed with the posterior tibial artery and concomitant vein as recipient vessels. STSGs were applied to cover the lattisimus dorsi (LD) free flap (Figure 3). The patient was then moved to the High Dependency Unit (HDU) and was closely monitored.

Figure 1 

47 yo woman, smoker, no medical comorbidities, foot injury after car accident.

Figure 2 

After multiple debridements and VAC.

Figure 3 

Free LD using end-to-end anastomosis with the posterior tibial (PT) artery.

Follow-up and outcome

On the first post-operative day, there were noted significant signs of venous congestion on the flap. Therefore, the patients was taken back to the operating room and the pedicle was explored. In order to treat the venous congestion, a 14 cm of saphenous vein was harvested from the contralateral leg and was used as a graft between the thoracodorsal vein and the great saphenous vein (Figure 4). However, on the 4th day, we noticed, during a dressing change, that the leg demonstrated signs of local infection, which resulted in total graph loss (Figure 5).

Figure 4 

Use of vein graft of the great saphenous vein form the contralateral leg because of venous congestion after using the PT vein.

Figure 5 

Postop infection and skin graft failure.

Conservative methods were followed until the 8th post-operative day, when we decided to use VAC therapy as a saving procedure. Vacuum dressings were applied over the flap and 50 mmHg of low pressure settings were selected (Figure 6). VAC dressings were changed every 36 hours and the flap was thoroughly monitored. Close monitoring of the flap ensured that there was not any signs of flap congestion, meanwhile the perfusion of the LD flap remained adequate.

Figure 6 

After skin graft debridement and application of VAC (low pressure 50 mmHg).

One week later, there was healthy granulation tissue formed over the muscle (Figure 7) and STSG was reapplied, using the VAC as a splint over the graft to prevent shear (Figure 8). Four days later, the wound was rechecked and more than 90% of the skin graft was successfully accepted in the deficit area.

Figure 7 

One week later, there was healthy granulation tissue formed over the muscle.

Figure 8 

STSG applied.

The flap had a 100% survival rate and there was no evidence of necrosis, while there was no need for revision surgeries. In the 3 months and 6 months follow-up the patient is able to walk and there was no episodes of infection or ulcer formation (Figure 9).

Figure 9 

Results after 3 months.


One of the most serious and crucial complications related to free tissue transfers is venous occlusion, which many times can be proven catastrophic. Venous thrombosis usually occurs first, leading to microcirculatory failure, which then evolves to arterial thrombosis and finally total graph loss [9].

Multiple factors can result to a total venous blockage such as haematoma formation, pedicle twisting, even thrombosis of the anastomosis [10]. As mentioned before, the venous anastomosis is the first region to form a clot, which then leads to the disruption of the microcirculation of the flap, leading to total graph loss.

Venous congestion can be subdivided to total or partial blockage. The initial treatment of partial venous congestion includes medicinal or chemical leaching, however total blockage requires thromboembolectomy or venous re-anastomosis of the flap [11]. In our case, the initial problem was the venous congestion of the LD flap. Firstly we applied conventional methods. Afterwards we inspected the vessels of the flap and venous anastomosis was reapplied by interposition of a vein graft, using the great saphenous vein of the contralateral leg, however the problem was not solved. Still, even though the artery was able to perfuse blood to the flap, the venous system was inadequate. As a result, the flap started to show signs of infection and necrosis.

We presumed that venous congestion had deteriorated, most likely due to the increased interstitial pressure. As a result, the application of VAC therapy in low negative pressure settings over the flap would remove the additional interstitial fluid. VAC therapy is described to decrease interstitial pressure, leading to the restoration of capillary perfusion and the achievement of blood flow to the flap. Even though, the physiological mechanisms involved need to be further examined, the practicality of the VAC therapy effects seem to explain the results. The period needed to achieve those results from VAC therapy are not quite obvious yet, however 6–7 days or a week seems like the ideal duration. During this time, neovascularisation of the flap would have occurred and venous outflow would be sufficient.

There were scarce literature findings that document the use of VAC therapy over a free flap, one was the use of VAC therapy over a superficial inferior-epigastric flap to third-degree burns on hand and fingers [12] and the other was over an anterolateral free flap used to cover deficits after wide excision of palmar contracture [13].

One thing that should always be considered is that the application of VAC therapy can add pressure on the flap, thus compressing it and creating an obstacle in its arterial flow. This should always be considered before initiating VAC therapy over a free tissue transfer. This is after all, the reason why most surgeons are reluctant to use VAC therapy on a free flap.

Conclusion – “Take away” lessons

In the end, it seems that VAC therapy may be an extra treatment option in cases where interstitial pressure rises over capillary pressure, leading to flap infection and flap loss. More studies need to be performed, in order to safeguard the efficacy and applicability of this tenchique.

Patient perpective

The patient was fully aware of the difficulty of the reconstruction. She was always informed about the interventions that we were implementing. However, most importantly, she was very compliant and followed our instructions closely which led to the best possible result.

Informed consent

The patient was informed and asked before the implementation of this case report and is fully aware and compliant with the scope of this study.

Funding Statement

There was no funding received for this paper.

Competing Interests

The authors have no competing interests to declare.

Author Contributions

  • Stamatis Sapountzis (Surgeons)
  • Georgios Karamitros (Surgeons)
  • Vasileios Goulios (Surgeons)
  • Ioannis Rallis (Surgeons)


Stamatis Sapountzis is the guarantor.

Peer Review

This is a non-commissioned paper that has undergone external peer review according to journal policy.


  1. Ubbink, DT, Westerbos, SJ, Evans, D, Land, L and Vermeulen, H. Topical negative pressure for treating chronic wounds. Cochrane Database Syst Rev. 2008 Jul 16; 3: CD001898. Review. Update In: Cochrane Database Syst Rev. 2015; 6: CD001898. PubMed PMID: 18646080. DOI: 

  2. Fleischmann, W, Strecker, W, Bombelli, M and Kinzl, L. Vacuum sealing as treatment of soft tissue damage in open fractures. Unfallchirurg. 1993 Sep; 96(9): 488–92. German. PubMed PMID: 8235687. 

  3. Morykwas, MJ, Argenta, LC, Shelton-Brown, EI, et al. Vacuum- assisted closure: A new method for wound control and treatment: Animal studies and basic foundation. Ann Plast Surg. 1997; 38: 553–562. DOI: 

  4. Argenta, LC and Morykwas, MJ. Vacuum-assisted closure: A new method for wound control and treatment: Clinical experience. Ann Plast Surg. 1997; 38: 563–577. DOI: 

  5. Greer, SE, Duthie, E, Cartolano, B, et al. Techniques for applying subatmospheric pressure dressing to wounds in difficult regions of anatomy. J Wound Ostomy Continence Nurs. 1999; 26: 250–253. 

  6. Miller, Q, Bird, E, Bird, K, et al. Effect of subatmospheric pressure on acute wound healing. Curr Surg. 2004; 61: 205–208. DOI: 

  7. Parrett, BM, Matros, E, Pribaz, JJ, et al. Lower extremity trauma: Trends in the management of soft tissue reconstruction of open tibia fibula fractures. Plast Reconstr Surg. 2006; 117: 1315. DOI: 

  8. Agha, RA, Fowler, AJ, Saeta, A, Barai, I, Rajmohan, S, Orgill, DP and SCARE Group. The SCARE Statement: Consensus-based surgical case report guidelines. Int J Surg. 2016 Oct; 34: 180–186. Epub 2016 Sep 7. Erratum In: Int J Surg. 2016 Dec; 36(Pt A): 396. Int J Surg. 2017 Nov; 47: 151. DOI: 

  9. Kerrigan, CL, Wizeman, P, Hjortdal, VE and Sampalis, J. Global flap ischemia: A comparison of arterial versus venous etiology. Plast Reconstr Surg. 1994; 93: 1485. DOI: 

  10. Urken, ML, Weinberg, H, Buchbinder, D, Moscoso, JF, Lawson, W, Catalano, PJ and Biller, HF. Microvascular free flaps in head and neck reconstruction: Report of 200 cases and review of complications. Arch Otolaryngol Head Neck Surg. 1994; 120: 633–40. DOI: 

  11. Akan, M, Yıldırım, S and Gideroglu, K. Salvage of flaps with venous congestion. Ann Plast Surg. 2001; 46: 456. DOI: 

  12. Weinand, C. The Vacuum-Assisted Closure (VAC) device for hastened attachment of a superficial inferior-epigastric flap to third-degree burns on hand and fingers. J Burn Care Res. 2009 Mar–Apr; 30(2): 362–5. PubMed PMID: 19242270. DOI: 

  13. Uygur, F, Duman, H, Ulkür, E and Ceiköz, B. The role of the vacuum-assisted closure therapy in the salvage of venous congestion of the free flap: Case report. Int Wound J. 2008 Mar; 5(1): 50–3. Epub 2008 Jan 3. PubMed PMID: 18179554. DOI: 

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